[Eyelid contact allergic eczema caused by topical ketorolac tromethamine 0.5%].
نویسندگان
چکیده
CLINICAL CASE A 65-year-old man had been treated with eye-drops containing NSAIDs (Ketorolac). He developed conjunctival injection, edematous swelling of the eyelids and periorbital dermatitis due to a contact allergy. Allergy to NSAIDs is uncommon. DISCUSSION This is an unusual case because topical application of ketorolac is safe in the vast majority of ophthalmologic patients. However adverse events associated with Ketorolac are similar to that of other NSAIDs.
منابع مشابه
Doubtful value of patch testing for suspected contact allergy to ophthalmic products.
Sir, Allergic contact dermatitis is the most common cause of peri-orbital eczema (1). It may be caused by allergens brought in contact with the eyelids by hand transfer (like toluene sulfonamide-formaldehyde resin in nail polishes), by airborne contact (like sesquiterpene lactones) or, most frequently, by direct application of cosmetics or topical ophthalmic medicaments. The percentage of sensi...
متن کاملLecithin - Stabilized Microemulsion: An Organogel for Topical Application of Ketorolac Tromethamine. I: Phase Behavior Studies
The partial phase behavior of systems composed of lecithin/isopropyl myristate (IPM)/water or ketorolac tromethamine (KT) solutions (2.5, 5, 10 and 50% w/w) at various lecithin/IPM weight ratios (km) have been investigated by the construction of phase diagrams. A commercially available soybean lecithin (namely, Epikuron 200, phosphatidylcholine purity greater than 95%) was used in this study. P...
متن کاملAnti-inflammatory and antiallergic eVects of ketorolac tromethamine in the conjunctival provocation model
Aim—To study the eVect of the topical anti-inflammatory drug, ketorolac, on (1) the clinical allergic reaction induced by the conjunctival provocation test (CPT); (2) the release of tryptase in tears; and (3) the expression of adhesion molecules on the conjunctival epithelium. Methods—10 allergic but non-active patients were challenged in both eyes with increasing doses of specific allergen to ...
متن کاملAnti-inflammatory and antiallergic effects of ketorolac tromethamine in the conjunctival provocation model.
AIM To study the effect of the topical anti-inflammatory drug, ketorolac, on (1) the clinical allergic reaction induced by the conjunctival provocation test (CPT); (2) the release of tryptase in tears; and (3) the expression of adhesion molecules on the conjunctival epithelium. METHODS 10 allergic but non-active patients were challenged in both eyes with increasing doses of specific allergen ...
متن کاملLecithin - Stabilized Microemulsion: An Organogel for Topical Application of Ketorolac Tromethamine. I: Phase Behavior Studies
The partial phase behavior of systems composed of lecithin/isopropyl myristate (IPM)/water or ketorolac tromethamine (KT) solutions (2.5, 5, 10 and 50% w/w) at various lecithin/IPM weight ratios (km) have been investigated by the construction of phase diagrams. A commercially available soybean lecithin (namely, Epikuron 200, phosphatidylcholine purity greater than 95%) was used in this study. P...
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ورودعنوان ژورنال:
- Archivos de la Sociedad Espanola de Oftalmologia
دوره 81 4 شماره
صفحات -
تاریخ انتشار 2006